Resource Type

Journal Article 324

Conference Videos 30

Conference Information 5

Year

2024 1

2023 24

2022 43

2021 25

2020 18

2019 33

2018 19

2017 11

2016 13

2015 10

2014 26

2013 8

2012 7

2011 17

2010 14

2009 6

2008 15

2007 8

2006 6

2005 4

open ︾

Keywords

traditional Chinese medicine 32

COVID-19 15

China 9

sustainable development 7

Traditional Chinese medicine 6

Chinese 5

Chinese medicine 4

Chinese herbal medicine 3

Chinese characteristics 2

Chinese cohort 2

Chinese herbal medicines 2

Chinese traditional culture 2

Coronavirus disease 2019 2

SARS-CoV-2 2

cancer 2

construction industry 2

development 2

development strategy 2

evidence-based medicine 2

open ︾

Search scope:

排序： Display mode:

Serum uric acid and risk of incident diabetes in middle-aged and elderly Chinese adults: prospectivecohort study

Di Cheng, Chunyan Hu, Rui Du, Hongyan Qi, Lin Lin, Xueyan Wu, Lina Ma, Kui Peng, Mian Li, Min Xu, Yu Xu, Yufang Bi, Weiqing Wang, Yuhong Chen, Jieli Lu

Frontiers of Medicine 2020, Volume 14, Issue 6,   Pages 802-810 doi: 10.1007/s11684-019-0723-7

Abstract: The association between serum uric acid and the risk of incident diabetes in Chinese adults remains unknownuric acid was associated with the increased risk of incident diabetes among middle-aged and elderly Chinese

Keywords： incident diabetes     prospective study     uric acid    

HTML PDF Collect

Chinese herbal medicine reduces mortality in patients with severe and critical coronavirus disease 2019: a retrospective cohort study

Guohua Chen, Wen Su, Jiayao Yang, Dan Luo, Ping Xia, Wen Jia, Xiuyang Li, Chuan Wang, Suping Lang, Qingbin Meng, Ying Zhang, Yuhe Ke, An Fan, Shuo Yang, Yujiao Zheng, Xuepeng Fan, Jie Qiao, Fengmei Lian, Li Wei, Xiaolin Tong

Frontiers of Medicine 2020, Volume 14, Issue 6,   Pages 752-759 doi: 10.1007/s11684-020-0813-6

Abstract: This study aimed to evaluate the efficacy of Chinese herbal medicine (CHM) in patients with severe/critical

Keywords： COVID-19     CHM     mortality     a retrospective cohort study    

HTML PDF Collect

fertility-sparing surgery for non-epithelial ovarian tumors to safely and successfully become pregnant---a Chineseretrospective cohort study among 148 cases

Bin Yang, Yan Yu, Jing Chen, Yan Zhang, Ye Yin, Nan Yu, Ge Chen, Shifei Zhu, Haiyan Huang, Yongqun Yuan, Jihui Ai, Xinyu Wang, Kezhen Li

Frontiers of Medicine 2018, Volume 12, Issue 5,   Pages 509-517 doi: 10.1007/s11684-017-0554-3

Abstract:

This study was performed to evaluate the oncological and reproductive outcomes of childbearing-age women treated with fertility-sparing surgery (FSS) for non-epithelial ovarian tumors in China. One hundred and forty eight non-epithelial ovarian tumor women treated with FSS between January 1, 2000 and August 31, 2015 from two medical centers in China were identified. Progression-free survival (PFS) was 88.5%, whereas overall survival (OS) was 93.9%. Univariate analysis suggested that delivery after treatment is related to PFS (P=0.023), whereas histology significantly influenced OS. Cox regression analysis suggested that only histology was associated with PFS and OS (P<0.05). Among the 129 women who completed adjuvant chemotherapy (ACT), none developed amenorrhea. Among the 44 women who desired pregnancy, 35 (79.5%) successfully had 51 gestations including 35 live births without birth defects. Non-epithelial ovarian tumors can achieve fulfilling prognosis after FSS and chemotherapy. Histology might be the only independent prognostic factor for PFS and OS. FSS followed by ACT appeared to have little or no effect on fertility. Meanwhile, postoperative pregnancy did not increase the PFS or OS. Use of gonadotropin-releasing hormone agonist was not beneficial for fertility.

Keywords： malignant germ cell tumors     ovarian sex cord-stromal tumors     fertility-sparing surgery     prognosis     fertility    

HTML PDF Collect

J-shaped association between dietary zinc intake and new-onset hypertension: a nationwide cohort study

Frontiers of Medicine 2023, Volume 17, Issue 1,   Pages 156-164 doi: 10.1007/s11684-022-0932-3

Abstract: We aimed to investigate the relationship of dietary zinc intake with new-onset hypertension among Chinesethere was a J-shaped association between dietary zinc intake and new-onset hypertension in general Chinese

Keywords： dietary zinc intake     new-onset hypertension     general population     CHNS    

HTML PDF Collect

of inactivated vaccine against SARS-CoV-2 infections in patients with comorbidities: a prospective cohort

Frontiers of Medicine   Pages 867-877 doi: 10.1007/s11684-023-0995-9

Abstract: Protection against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection of inactivated vaccines is not well characterized in people with comorbidities, who are at high risk of severe infection. We compared the risk of SARS-CoV-2 infection after complete vaccination with Sinopharm/BBIBP in people with comorbidities (e.g., autoimmune diseases, cardiovascular disease, chronic lung disease, and diabetes) with healthy individuals using a Cox-proportional hazard model. In July–September 2021, a total of 10 548 people (comorbidities, 2143; healthy, 8405) receiving the complete primary series of vaccination with Sinopharm/BBIBP in Bangkok, Thailand were prospectively followed for SARS-CoV-2 infection through text messaging and telephone interviewing for 6 months. A total of 295 infections from 284 participants were found. HRs (95% CI) of individuals with any comorbidities did not increase (unadjusted, 1.02 (0.77–1.36), P = 0.89; adjusted, 1.04 (0.78–1.38), P = 0.81). HRs significantly increased in the subgroup of autoimmune diseases (unadjusted, 2.64 (1.09–6.38), P = 0.032; adjusted, 4.45 (1.83–10.83), P = 0.001) but not in cardiovascular disease, chronic lung disease, or diabetes. The protection against SARS-CoV-2 infection of the Sinopharm vaccine was similar in participants with any comorbidities vs. healthy individuals. However, the protection appeared lower in the subgroup of autoimmune diseases, which may reflect suboptimal immune responses among these people.

Keywords： COVID-19     Sinopharm/BBIBP vaccine     immunocompromised patients     real-world    

HTML PDF Collect

fatty liver disease with elevated brachial-ankle pulse wave velocity and albuminuria: a prospective cohort

Frontiers of Medicine 2022, Volume 16, Issue 5,   Pages 714-722 doi: 10.1007/s11684-021-0888-8

Abstract: A new definition of metabolic dysfunction-associated fatty liver disease (MAFLD) has recently been proposed. We aim to examine the associations of MAFLD, particularly its discordance from non-alcoholic fatty liver disease (NAFLD), with the progression of elevated brachial-ankle pulse wave velocity (baPWV) and albuminuria in a community-based study sample in Shanghai, China. After 4.3 years of follow-up, 778 participants developed elevated baPWV and 499 developed albuminuria. In comparison with the non-MAFLD group, the multivariable adjusted odds ratio (OR) of MAFLD group for new-onset elevated baPWV was 1.25 (95% confidence interval (CI) 1.01–1.55) and 1.35 (95% CI 1.07–1.70) for albuminuria. Participants without NAFLD but diagnosed according to MAFLD definition were associated with higher risk of incident albuminuria (OR 1.77; 95% CI 1.07–2.94). Patients with MAFLD with high value of hepamet fibrosis score or poor-controlled diabetes had higher risk of elevated baPWV or albuminuria. In conclusion, MAFLD was associated with new-onset elevated baPWV and albuminuria independently of body mass index, waist circumference, and hip circumference. Individuals without NAFLD but diagnosed as MAFLD had high risk of albuminuria, supporting that MAFLD criteria would be practical for the evaluation of long-term risk of subclinical atherosclerosis among fatty liver patients.

Keywords： metabolic dysfunction-associated fatty liver disease     non-alcoholic fatty liver disease     fibrosis score     brachial-ankle pulse wave velocity     albuminuria    

HTML PDF Collect

Association of maternal depression with dietary intake, growth, and development of preterm infants: a cohort

Han Wang, Hong Zhou, Yan Zhang, Yan Wang, Jing Sun

Frontiers of Medicine 2018, Volume 12, Issue 5,   Pages 533-541 doi: 10.1007/s11684-017-0591-y

Abstract: A cohort study of 201 infants was conducted in Beijing.

Keywords： maternal depression     preterm     infant     nutrition     growth     development    

HTML PDF Collect

characteristics and risk factors of COVID-19 patients with chronic hepatitis B: a multi-center retrospective cohort

Frontiers of Medicine 2022, Volume 16, Issue 1,   Pages 111-125 doi: 10.1007/s11684-021-0854-5

Abstract: In this multi-center, retrospective, and observational cohort study, 109 CHB and 327 non-CHB patients

Keywords： COVID-19     chronic hepatitis B     liver injury     coagulation dysfunction    

HTML PDF Collect

Long-term exposure to air pollution and cerebrovascular disease: findings from Beijing Health Management Cohort

Frontiers of Environmental Science & Engineering 2023, Volume 17, Issue 7, doi: 10.1007/s11783-023-1684-2

Abstract:

● This study explored the long-term association by double robust additive models.

Keywords： Air pollution     Cerebrovascular disease     Incidence     Long-term exposure     Doubly robust additive model    

HTML PDF Collect

Hospital-Based Phenotypic Features and Treatment Outcomes of Chinese Women with Polycystic Ovary Syndrome Article

Jingshu Gao, Hongli Ma, Yu Wang, Xinming Yang, Yijuan Cao, Bei Zhang, Conghui Han, Xiaoke Wu

Engineering 2021, Volume 7, Issue 2,   Pages 170-177 doi: 10.1016/j.eng.2020.12.006

Abstract: secondary analysis of a large-sample, multicenter, randomized controlled trial conducted at 21 sites in Chinese

Keywords： Polycystic ovary syndrome     Body mass index     Phenotype     Chinese cohort     Geographic distribution    

HTML PDF Collect

mortality of V-V ECMO-supported patients—the ECMO quality improvement action (EQIA) study: a national cohort

Frontiers of Medicine doi: 10.1007/s11684-023-1014-x

Abstract: This cohort study was performed to explore the influence of intensive care unit (ICU) quality on in-hospital

Keywords： veno-venous extracorporeal membrane oxygenation     in-hospital mortality     high-volume centers     quality control     intensive care unit capacity parameters    

HTML PDF Collect

Cohort-based personalized query auto-completion Regular Papers-Research Articles

Dan-yang JIANG, Hong-hui CHEN

Frontiers of Information Technology & Electronic Engineering 2019, Volume 20, Issue 9,   Pages 1246-1258 doi: 10.1631/FITEE.1800010

Abstract: As conventional topic models are unable to automatically learn cohorts, we propose two cohort topic modelsthat handle topic modeling and cohort discovery in the same framework.We present four cohortbased personalized QAC models that employ four different cohort discovery strategiespublicly available AOL query log and compare the ranking effectiveness with that of models that discard cohortExperimental results suggest that our cohort-based personalized QAC models can solve the sparseness problem

Keywords： Query auto-completion     Cohort-based retrieval     Topic models    

HTML PDF Collect

An Evaluation Method of Human Gut Microbial Homeostasis by Testing Specific Fecal Microbiota Article

Zhongwen Wu, Xiaxia Pan, Yin Yuan, Pengcheng Lou, Lorina Gordejeva, Shuo Ni, Xiaofei Zhu, Bowen Liu, Lingyun Wu, Lanjuan Li, Bo Li

Engineering 2023, Volume 29, Issue 10,   Pages 110-119 doi: 10.1016/j.eng.2023.03.007

Abstract: groups of gut bacteria that characterized the whole microbiome in the human gut from a largesample Chinesecohort, constructed a real-time quantitative polymerase chain reaction (qPCR) method and developed a

Keywords： Gut microbiota     Machine learning     Microbial dysbiosis     Quantitative polymerase chain reaction     Chinesecohort    

HTML PDF Collect

5p and urinary albumin excretion rates in patients with type 2 diabetes mellitus: a cross-sectional cohort

Huiwen Ren, Can Wu, Ying Shao, Shuang Liu, Yang Zhou, Qiuyue Wang

Frontiers of Medicine 2020, Volume 14, Issue 5,   Pages 642-650 doi: 10.1007/s11684-019-0719-3

Abstract: This study aimed to investigate the correlation between serum miR-154-5p and urinary albumin to creatinine ratio (UACR) in patients with type 2 diabetes mellitus (T2DM) and the association with biomarkers of inflammation and fibrosis in diabetic kidney disease (DKD). A total of 390 patients with T2DM were divided into three groups: normal albuminuria (UACR<30 mg/g, =136, NA), microalbuminuria (UACR at 30–300 mg/g, =132, MA), and clinical albuminuria (UACR>300 mg/g, =122, CA). Circulating miR-154-5p, inflammatory (C-reactive protein (CRP); erythrocyte sedimentation rate (ESR); and tumor necrosis factor-α (TNF-α) and fibrotic markers (vascular endothelial growth factor (VEGF); transforming growth factor-β1 (TGF-β1); and fibronectin (FN)), and other biochemical indicators were assessed via real-time PCR, enzyme-linked immunosorbent assay, and chemiluminescence assay in patients with T2DM and 138 control subjects (NC). UACR, miR-154-5p, glycated hemoglobin (HbA1c), serum creatinine (sCr), blood urea nitrogen (BUN), ESR, CRP, VEGF, TNF-α, TGF-β1, and FN were significantly higher and the estimated glomerular filtration rate (eGFR) was significantly lower in NA, MA, and CA groups than in NC subjects ( <0.05). Elevated levels of UACR and miR-154-5p were directly correlated with HbA1c, sCr, BUN, ESR, CRP, VEGF, TNF-α, TGF-β1, and FN and negatively correlated with eGFR ( <0.05). miR-154-5p, HbA1c, sCr, BUN, eGFR, ESR, CRP, VEGF, TNF-α, TGF-β1, and FN were important factors affecting UACR. These findings indicated that elevated serum miR-154-5p is significantly correlated with high UACR in patients with T2DM and may offer a novel reference for the early diagnosis of DKD.

Keywords： type 2 diabetes mellitus     diabetic kidney disease     miR-154-5p     urinary albumin to creatinine ratio    

HTML PDF Collect

Practice and principle of traditional Chinese medicine for the prevention and treatment of COVID-19

Frontiers of Medicine doi: 10.1007/s11684-023-1040-8

Abstract: Traditional Chinese medicine (TCM) has played an important role in the prevention and treatment of coronavirusThe integration of Chinese and Western medicine is an important feature of Chinese COVID-19 prevention

Keywords： traditional Chinese medicine     COVID-19     SARS-CoV-2     clinical evidence-based study     mechanism     integratedtraditional Chinese and Western medicine    

HTML PDF Collect

Title Author Date Type Operation

Serum uric acid and risk of incident diabetes in middle-aged and elderly Chinese adults: prospectivecohort study

Di Cheng, Chunyan Hu, Rui Du, Hongyan Qi, Lin Lin, Xueyan Wu, Lina Ma, Kui Peng, Mian Li, Min Xu, Yu Xu, Yufang Bi, Weiqing Wang, Yuhong Chen, Jieli Lu

Journal Article

Chinese herbal medicine reduces mortality in patients with severe and critical coronavirus disease 2019: a retrospective cohort study

Guohua Chen, Wen Su, Jiayao Yang, Dan Luo, Ping Xia, Wen Jia, Xiuyang Li, Chuan Wang, Suping Lang, Qingbin Meng, Ying Zhang, Yuhe Ke, An Fan, Shuo Yang, Yujiao Zheng, Xuepeng Fan, Jie Qiao, Fengmei Lian, Li Wei, Xiaolin Tong

Journal Article

fertility-sparing surgery for non-epithelial ovarian tumors to safely and successfully become pregnant---a Chineseretrospective cohort study among 148 cases

Bin Yang, Yan Yu, Jing Chen, Yan Zhang, Ye Yin, Nan Yu, Ge Chen, Shifei Zhu, Haiyan Huang, Yongqun Yuan, Jihui Ai, Xinyu Wang, Kezhen Li

Journal Article

J-shaped association between dietary zinc intake and new-onset hypertension: a nationwide cohort study

Journal Article

of inactivated vaccine against SARS-CoV-2 infections in patients with comorbidities: a prospective cohort

Journal Article

fatty liver disease with elevated brachial-ankle pulse wave velocity and albuminuria: a prospective cohort

Journal Article

Association of maternal depression with dietary intake, growth, and development of preterm infants: a cohort

Han Wang, Hong Zhou, Yan Zhang, Yan Wang, Jing Sun

Journal Article

characteristics and risk factors of COVID-19 patients with chronic hepatitis B: a multi-center retrospective cohort

Journal Article

Long-term exposure to air pollution and cerebrovascular disease: findings from Beijing Health Management Cohort

Journal Article

Hospital-Based Phenotypic Features and Treatment Outcomes of Chinese Women with Polycystic Ovary Syndrome

Jingshu Gao, Hongli Ma, Yu Wang, Xinming Yang, Yijuan Cao, Bei Zhang, Conghui Han, Xiaoke Wu

Journal Article

mortality of V-V ECMO-supported patients—the ECMO quality improvement action (EQIA) study: a national cohort

Journal Article

Cohort-based personalized query auto-completion

Dan-yang JIANG, Hong-hui CHEN

Journal Article

An Evaluation Method of Human Gut Microbial Homeostasis by Testing Specific Fecal Microbiota

Zhongwen Wu, Xiaxia Pan, Yin Yuan, Pengcheng Lou, Lorina Gordejeva, Shuo Ni, Xiaofei Zhu, Bowen Liu, Lingyun Wu, Lanjuan Li, Bo Li

Journal Article

5p and urinary albumin excretion rates in patients with type 2 diabetes mellitus: a cross-sectional cohort

Huiwen Ren, Can Wu, Ying Shao, Shuang Liu, Yang Zhou, Qiuyue Wang

Journal Article

Practice and principle of traditional Chinese medicine for the prevention and treatment of COVID-19

Journal Article